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The findings add to the growing body of evidence that getting heavier is not just a matter of “calories in, calories out,” and that the mantra: “Eat less and exercise more” is far too simplistic. Although calories remain crucial, some foods clearly cause people to put on more weight than others, perhaps because of their chemical makeup and how our bodies process them. This understanding may help explain the dizzying, often seemingly contradictory nutritional advice from one dietary study to the next.