The short answer, I think (hope) is, "Yes." Will it happen? Could it be a woman of color? Could it be a woman of color who openly identifies as LGBTQ+? Well, again, I hope the answer is "yes" on all fronts.
Am I naive? I'm sure those scenarios would spark some reactionary comments from some factions of fandom ... but would it overwhelm the show or hurt the ratings, all other things being equal?